The LHC is an ordered array of sensors that detect very high-energy interactions with those sensors, no "particles" required (any more than you could say a radio "detects" photons)
Cryogenics and vacuum chambers seem unnecessary considering that zero point energy means it can't be eliminated and, in any event, no amount of shielding will prevent errant energy, as is acknowledged with muons/neutrinos (going in other direction). So then we get into the potentially dubious area of "outliers" and data "cleaning."