Seeking truth has always been central to philosophy, tied intrinsically to conceptions of knowledge and being. But discordant claims of truth often emerge between cultures, traditions, and schools of thought. This confrontation becomes most pointed when assertions about the nature of reality and humanity’s place within it fundamentally diverge or contradict one another. How can we make sense of these incongruities? First, meticulously examine the logic, factual evidence and reasoning behind each claim. This analysis may reveal one view as more rationally convincing or expose flaws in untenable arguments. However, as most philosophies deal with interpretations about existence itself, empirical proofs are elusive. Thus, cogency of reasoning is our best evaluative lodestar. Next, reflect deeply on the historical and contextual factors that shaped each worldview. Insights into their origins expose why divergence emerged and the cultural values infusing varying interpretations. Truth is often colored by the lens of place and time. Also seek commonalities between perspectives which point to shared truths. For instance, the virtue of compassion is universally proclaimed. Differing manifestations of core principles can enlighten. Furthermore, accept that ambiguities and enigmas will persist. Demanding definitive resolutions often stems from hubris and anxiety. Making peace with uncertainty allows embracing truth’s manifold complexity. Synthesis constitutes a powerful tool. Integrating valid realizations from opposing viewpoints unveils grander vistas of truth, just as thesis and antithesis yield synthesis. The whole transcends fragmented parts. Since absolute truth may be ineffable, assessing pragmatic value provides guidance. Ideas that positively impact humanity likely contain elements of wisdom, whatever their metaphysical status. Cultivating empathy and occupying divergent mental spaces also hones discernment. Inhabiting each worldview’s internal reasoning lets truth reveal itself multidimensionally. Ultimately, reconciling contradictory claims heightens understanding of truth’s nuance. And sharpening one’s own interpretations through constant self-reflection is the greatest catalyst for wisdom.